Investing in the Global Fund, Today and Tomorrow

We welcome today’s strong U.S. pledge of $4.6 billion for the Global Fund to Fight AIDS, Tuberculosis and Malaria and its commitment to continue matching contributions from other donors at rate of $1 for every $2 invested.  

With U.S. leadership, and commitments from countries and private and philanthropic donors, the international community came together in a strong show of support for the Global Fund’s lifesaving work. As of November 21, donors pledged $11.34 billion for the Global Fund’s next three-year strategy. 

The Replenishment Summit comes on the heels of a busy few months for the Global Fund. At the UN General Assembly, the Gates Foundation pledged $912 million, further cementing its place as the Global Fund’s largest private donor and bringing private-sector pledges above the $1 billion mark. At the World Health Summit in Berlin, Germany also pledged $1 billion for the Global Fund over the next two years.  

Here in the U.S., the House’s foreign affairs funding bill for FY26, introduced in July 2025, included funding for the Global Fund. The State Department also released its America First Global Health Strategy, acknowledging Global Fund’s investment in American innovation to fight the world’s deadliest diseases.  

The U.S. pledge in Johannesburg shows that the Administration is serious about following through on its proposals, even amid a global landscape of declining foreign aid budgets.  

Undersecretary of State Jeremy Lewin noted in his pledge announcement that “the Global Fund is a critical partner in advancing the America First Global Health Strategy,” with its world-class pooled procurement mechanism, its investment in building sustainable health systems, and requirements for co-financing and cost-sharing.  

Many traditional donors have made smaller commitments than in previous years. Germany’s $1 billion contribution is substantial and sorely needed, but it represents a decrease from their previous pledge. The UK, despite co-hosting the replenishment summit, has also pared back its contribution, while traditional donors France and Japan have postponed their pledges.  

While the U.S. pledge has also declined from previous years, it will continue to match every $2 pledged from other countries with $1 of its own—both amplifying the impact of each investment and demonstrating America’s continued leadership in global health.  

At a time when even the smallest disruption can set back progress against malaria, it’s crucial that countries continue to support the vital work of the Global Fund. We are at a tipping point in the malaria fight. From rising resistance to drugs and insecticides to extreme weather impacts, the potential for a deadly resurgence of malaria is real. 

Supporting the Global Fund’s vision for the next few years is the right call—for the world and for the U.S.  

While the total pledge fell short and several donors have yet to confirm pledges, these commitments still underscore that the Global Fund is a key supporter of countries’ health system strengthening efforts, and full funding would help make countries even more resilient and able to lead in the fight against malaria. When it comes to lives saved, illness prevented, costs averted, and country health systems strengthened, the Global Fund is an unbeatable investment.  

As advocates, we’re proud to continue raising awareness and support for the Global Fund on our home turf. We call on Congress to follow through on America’s commitment and fully back the Global Fund in FY26 and beyond.