Innovation

Emile Dawisha

April 16, 2024

Part 10 of our Malaria Gamechangers series (check out Episodes 1-9) highlights outdoor mosquito management. Controlling mosquito populations, from the larval to the adult stage, has long been a cornerstone of local, regional, and country-level efforts to combat malaria, along with other mosquito-borne diseases like West Nile, dengue, Zika, and yellow fever. It takes an … Continued

Emile Dawisha

January 23, 2024

The 2023 World Malaria Report revealed that, following significant setbacks during the COVID-19 pandemic, malaria rates have stabilized in many respects. Nevertheless, malaria cases and deaths remain higher than they were pre-pandemic, in part due to growing drug and insecticide resistance, rising rates of humanitarian crises and displacement, an invasive new mosquito species in the African continent, among other threats. And yet, … Continued

Emile Dawisha

August 10, 2023

Part 9 of our Malaria Gamechangers series (check out Episodes 1-8) highlights the RTS,S/AS01 [RTS,S] malaria vaccine, the first-ever malaria vaccine to receive World Health Organization (WHO) approval for widespread use. Developed by GSK, RTS,S has already been administered to nearly 1.7 million children through pilots in Kenya, Ghana, and Malawi. The 4-dose vaccine has shown to reduce … Continued

Emile Dawisha

June 28, 2023

Part 8 of our Malaria Gamechangers series (check out Episodes 1-7) highlights the development of monoclonal antibodies for malaria prevention. Many associate monoclonal antibody drugs with the COVID-19 pandemic. These man-made proteins, which act like human antibodies and offer passive immunity, hold tremendous potential well beyond COVID-19. In recent years, antibody candidates have emerged for … Continued

Emile Dawisha

June 1, 2023

Part 7 of our Malaria Gamechangers series (check out Episodes 1-6) highlights innovative, low-cost spatial repellent products that have shown to safely protect homes from malaria for up to 12 months. Developed by SC Johnson, these new products – Guardian™ and Shield™ – create a protective shield against mosquitoes, using natural air flow to passively … Continued

Emile Dawisha

May 25, 2023

Part 6 of our Malaria Gamechangers series (check out Episodes 1-5) highlights the R21/Matrix-M™ [R21] malaria vaccine, a high-efficacy malaria vaccine targeting young children who are most vulnerable to the disease. Developed by the University of Oxford’s Jenner Institute, R21 is currently in the late stages of clinical trials and has demonstrated promising results thus … Continued

Emile Dawisha

May 17, 2023

Part 5 of our Malaria Gamechangers series (check out Episodes 1-4) highlights seasonal malaria chemoprevention (SMC), a highly-effective method of protecting young children from malaria during peak malaria transmission season. SMC involves giving children, ages 3 months to 5 years, a monthly course of safe and effective anti-malarial drugs (a combination of sulfadoxine-pyrimethamine and amodiaquine) … Continued

Emile Dawisha

May 11, 2023

Part 4 of our Malaria Gamechangers series (check out Episodes 1-3) highlights a new family of malaria medicines being developed to combat the growing threat of anti-malarial drug resistance. Throughout history, malaria drugs have repeatedly been compromised by antimicrobial resistance. In the wake of widespread Chloroquine resistance, artemisinin-based combination therapy (ACT) has become the first-line … Continued

Emile Dawisha

May 3, 2023

Part 3 of our Malaria Gamechangers series (check out Episodes 1 and 2) highlights a next-generation indoor residual spraying (IRS) product, Envu’s Fludora® Fusion, that safely protects homes from malaria for up to one year and is proven effective against insecticide-resistant mosquitoes and on 33 different surfaces. The WHO-prequalified product is the first IRS spray to combine … Continued

Emile Dawisha

April 26, 2023

Part 2 of our Malaria Gamechangers series (check out Part 1) focuses on next-generation bed nets that use insecticide combinations to combat the emerging threat of pyrethroid resistance. Specifically, we highlight the efforts of BASF and a group of partners – Innovative Vector Control Consortium (IVCC), Unitaid, the Bill & Melinda Gates Foundation, MedAccess, and … Continued